Disease Post

Fibrodysplasia Ossificans Progressiva

symptoms

FOP often begins in the neck and shoulders and progresses along the back, trunk, and limbs of the body. Malformed big toes are always correlated with the condition and can be observed as early as birth. Another symptom is that rather than crawl with their hands and knees, most kids with FOP scoot on their butt; then get up and walk. Although FOP starts before birth, the extra bone does not form before birth only after birth. Other symptoms of FOP, including bone formation (usually begin during the first two decades of life), Inflamed and sometimes-painful swellings, typically in the shoulder and back areas and sometimes on the scalp or head, are usually the first sign of FOP. The swellings eventually clear up, but they leave behind a new piece of mature bone. In each case, the exact rate of progression is not predictable, but there appears to be a pattern to the progression.

 outlook 

FOP is a very rare disorder, believed to occur in approximately 1 in 2 million people worldwide. Only Several hundred cases have been reported. This condition can be inherited because of one copy of the altered gene in each cell is sufficient to cause the disorder. These cases occur in people with no history of the disorder in their family. In a small number of cases, an affected person has inherited the mutation from one affected parent. Fibrodysplasia ossificans progressiva has a poor prognosis.

 

symptoms

FOP often begins in the neck and shoulders and progresses along the back, trunk, and limbs of the body. Malformed big toes are always correlated with the condition and can be observed as early as birth. Another symptom is that rather than crawl with their hands and knees, most kids with FOP scoot on their butt; then get up and walk. Although FOP starts before birth, the extra bone does not form before birth only after birth. Other symptoms of FOP, including bone formation (usually begin during the first two decades of life), Inflamed and sometimes-painful swellings, typically in the shoulder and back areas and sometimes on the scalp or head, are usually the first sign of FOP. The swellings eventually clear up, but they leave behind a new piece of mature bone. In each case, the exact rate of progression is not predictable, but there appears to be a pattern to the progression.

  treatments

Doctors that may help:

• Neuromusculoskeletal Medicine
• Orthopedic Surgery
• Family Practice
• Pediatrics (Child Health Specialist)
• Adolescent Medicine (Teen Health)
• Geriatric Medicine (Senior Health)
• Internal Medicine

 

There is no successful cure for FOP but it is hoped that future studies will pinpoint the mutation occurring in FOP and lead to a better understanding of the disease’s mechanism. Fibrodysplasia ossificans progressiva has a poor prognosis.

 

http://ghr.nlm.nih.gov/condition/fibrodysplasia-ossificans-progressiva

http://www.ifopa.org/fop-fact-sheet.html